The look for differentially-methylated locations utilizing bisulfite-transformed DNA (Circle 3 in Figure 1) could possibly be accomplished Along with the use of various techniques. Some of them are simpler to perform and analyse than Other individuals, mainly because only a fraction from the genome is utilized. The most pronounced purposeful influe
. this sort of experiments are identified as mutation accumulation (MA) experiments (Elena and Lenski 2003; Lind and Andersson 2008; Brockhurst et al. 2010). now it is doable to stick to up MA experiments with total-genome sequencing on the ancestor strain and its ensuing progeny, Therefore allowing for for the genome-extensive identification of th
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